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Controlling AOX1 promoter strength in Pichia pastoris by manipulating poly (dA:dT) tracts

Alcohol oxidase I (AOX1) promoter is the most popular but strictly-regulated methanol inducible promoter for heterologous protein expression in Pichia pastoris. In recent years, AOX1 promoter libraries have been developed with deletion or insertion methods. The present research manipulated poly (dA:...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Yang, Jun, Cai, Haiming, Liu, Jie, Zeng, Min, Chen, Jiawei, Cheng, Qingmei, Zhang, Linghua
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780452/
https://ncbi.nlm.nih.gov/pubmed/29362428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19831-y
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