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Controlling AOX1 promoter strength in Pichia pastoris by manipulating poly (dA:dT) tracts

Alcohol oxidase I (AOX1) promoter is the most popular but strictly-regulated methanol inducible promoter for heterologous protein expression in Pichia pastoris. In recent years, AOX1 promoter libraries have been developed with deletion or insertion methods. The present research manipulated poly (dA:...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Yang, Jun, Cai, Haiming, Liu, Jie, Zeng, Min, Chen, Jiawei, Cheng, Qingmei, Zhang, Linghua
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5780452/
https://ncbi.nlm.nih.gov/pubmed/29362428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19831-y
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