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Tubastatin A Prevents Hemorrhage-Induced Endothelial Barrier Dysfunction
BACKGROUND: Microvascular hyperpermeability resulting from endothelial barrier dysfunction (EBD) is associated with worse clinical outcomes in trauma-induced hemorrhagic shock. We have previously shown that treatment with Tubastatin A (TubA), a histone deacetylase 6 inhibitor, improves outcomes in a...
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| Publicado no: | J Trauma Acute Care Surg |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5780204/ https://ncbi.nlm.nih.gov/pubmed/29194316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0000000000001753 |
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