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Comparison of T cell activities mediated by human TCRs and CARs that use the same recognition domains
Adoptive T cell therapies have achieved significant clinical responses, especially in hematopoietic cancers. Two types of receptor systems have been used to redirect the activity of T cells, normal heterodimeric T-cell receptors (TCRs) or synthetic chimeric antigen receptors (CARs). TCRs recognize p...
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Publicado no: | J Immunol |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5780198/ https://ncbi.nlm.nih.gov/pubmed/29288199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700236 |
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