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Cranial irradiation inhibits hippocampal neurogenesis via DNMT1 and DNMT3A
Impairment of neurogenesis in the hippocampus following whole-brain irradiation is the most important mechanism of radiation-induced cognitive dysfunction. However, the underlying mechanism remains obscure, meaning an ideal therapeutic target has not been identified. Evidence indicates that DNA meth...
Enregistré dans:
| Publié dans: | Oncol Lett |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
D.A. Spandidos
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5778827/ https://ncbi.nlm.nih.gov/pubmed/29435016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7643 |
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