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Cranial irradiation inhibits hippocampal neurogenesis via DNMT1 and DNMT3A

Impairment of neurogenesis in the hippocampus following whole-brain irradiation is the most important mechanism of radiation-induced cognitive dysfunction. However, the underlying mechanism remains obscure, meaning an ideal therapeutic target has not been identified. Evidence indicates that DNA meth...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Ji, Shengjun, Ding, Xin, Ji, Jiang, Wu, Haohao, Sun, Rui, Li, Xiaoyang, Zhang, Liyuan, Tian, Ye
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778827/
https://ncbi.nlm.nih.gov/pubmed/29435016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7643
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