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Editing activity for eliminating mischarged tRNAs is essential in mammalian mitochondria
Accuracy of protein synthesis is enabled by the selection of amino acids for tRNA charging by aminoacyl-tRNA synthetases (ARSs), and further enhanced by the proofreading functions of some of these enzymes for eliminating tRNAs mischarged with noncognate amino acids. Mouse models of editing-defective...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5778596/ https://ncbi.nlm.nih.gov/pubmed/29228266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1231 |
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