Truncated HSPB1 causes axonal neuropathy and impairs tolerance to unfolded protein stress

BACKGROUND: HSPB1 belongs to the family of small heat shock proteins (sHSP) that have importance in protection against unfolded protein stress, in cancer cells for escaping drug toxicity stress and in neurons for suppression of protein aggregates. sHSPs have a conserved α-crystalline domain (ACD), f...

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Detalles Bibliográficos
Publicado en:BBA Clin
Main Authors: Ylikallio, Emil, Konovalova, Svetlana, Dhungana, Yogesh, Hilander, Taru, Junna, Nella, Partanen, Juhani V., Toppila, Jussi P., Auranen, Mari, Tyynismaa, Henna
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2015
Assuntos:
Regular Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661565/
https://ncbi.nlm.nih.gov/pubmed/26675522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbacli.2015.03.002
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