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Truncated HSPB1 causes axonal neuropathy and impairs tolerance to unfolded protein stress

BACKGROUND: HSPB1 belongs to the family of small heat shock proteins (sHSP) that have importance in protection against unfolded protein stress, in cancer cells for escaping drug toxicity stress and in neurons for suppression of protein aggregates. sHSPs have a conserved α-crystalline domain (ACD), f...

詳細記述

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書誌詳細
出版年:BBA Clin
主要な著者: Ylikallio, Emil, Konovalova, Svetlana, Dhungana, Yogesh, Hilander, Taru, Junna, Nella, Partanen, Juhani V., Toppila, Jussi P., Auranen, Mari, Tyynismaa, Henna
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661565/
https://ncbi.nlm.nih.gov/pubmed/26675522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbacli.2015.03.002
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