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Truncated HSPB1 causes axonal neuropathy and impairs tolerance to unfolded protein stress
BACKGROUND: HSPB1 belongs to the family of small heat shock proteins (sHSP) that have importance in protection against unfolded protein stress, in cancer cells for escaping drug toxicity stress and in neurons for suppression of protein aggregates. sHSPs have a conserved α-crystalline domain (ACD), f...
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| 出版年: | BBA Clin |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4661565/ https://ncbi.nlm.nih.gov/pubmed/26675522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbacli.2015.03.002 |
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