Conformational heterogeneity and bubble dynamics in single bacterial transcription initiation complexes

Transcription initiation is a major step in gene regulation for all organisms. In bacteria, the promoter DNA is first recognized by RNA polymerase (RNAP) to yield an initial closed complex. This complex subsequently undergoes conformational changes resulting in DNA strand separation to form a transc...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Duchi, Diego, Gryte, Kristofer, Robb, Nicole C, Morichaud, Zakia, Sheppard, Carol, Brodolin, Konstantin, Wigneshweraraj, Sivaramesh, Kapanidis, Achillefs N
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778504/
https://ncbi.nlm.nih.gov/pubmed/29177430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1146
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