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High Levels of Cyclic Di-GMP in Klebsiella pneumoniae Attenuate Virulence in the Lung

The bacterial second messenger bis-(3′-5′)-cyclic dimeric GMP (c-di-GMP) has been shown to influence the expression of virulence factors in certain pathogenic bacteria, but little is known about its activity in the increasingly antibiotic-resistant pathogen Klebsiella pneumoniae. Here, the expressio...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Rosen, David A., Twentyman, Joy, Hunstad, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778367/
https://ncbi.nlm.nih.gov/pubmed/29158434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00647-17
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