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Cyclic Di-GMP Receptor PlzA Controls Virulence Gene Expression through RpoS in Borrelia burgdorferi

As an obligate pathogen, the Lyme disease spirochete Borrelia burgdorferi has a streamlined genome that encodes only two two-component signal transduction systems, Hk1-Rrp1 and Hk2-Rrp2 (in addition to CheA-CheY systems). The output of Hk1-Rrp1 is the production of the second messenger cyclic di-GMP...

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Detalles Bibliográficos
Main Authors: He, Ming, Zhang, Jun-Jie, Ye, Meiping, Lou, Yongliang, Yang, X. Frank
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911845/
https://ncbi.nlm.nih.gov/pubmed/24218478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01238-13
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