Analysis of the Borrelia burgdorferi Cyclic-di-GMP-Binding Protein PlzA Reveals a Role in Motility and Virulence

The cyclic-dimeric-GMP (c-di-GMP)-binding protein PilZ has been implicated in bacterial motility and pathogenesis. Although BB0733 (PlzA), the only PilZ domain-containing protein in Borrelia burgdorferi, was reported to bind c-di-GMP, neither its role in motility or virulence nor it's affinity...

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Bibliografiset tiedot
Päätekijät: Pitzer, Joshua E., Sultan, Syed Z., Hayakawa, Yoshihiro, Hobbs, Gerry, Miller, Michael R., Motaleb, Md A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2011
Aiheet:
Molecular Pathogenesis
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088147/
https://ncbi.nlm.nih.gov/pubmed/21357718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00075-11
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