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Analysis of the HD-GYP Domain Cyclic Dimeric GMP Phosphodiesterase Reveals a Role in Motility and the Enzootic Life Cycle of Borrelia burgdorferi

HD-GYP domain cyclic dimeric GMP (c-di-GMP) phosphodiesterases are implicated in motility and virulence in bacteria. Borrelia burgdorferi possesses a single set of c-di-GMP-metabolizing enzymes, including a putative HD-GYP domain protein, BB0374. Recently, we characterized the EAL domain phosphodies...

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Detalhes bibliográficos
Main Authors: Sultan, Syed Z., Pitzer, Joshua E., Boquoi, Tristan, Hobbs, Gerry, Miller, Michael R., Motaleb, M. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147568/
https://ncbi.nlm.nih.gov/pubmed/21670168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05153-11
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