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HD-[HD-GYP] Phosphodiesterases: Activities and Evolutionary Diversification within the HD-GYP Family

Cyclic dinucleotides are signaling molecules that modulate many processes, including immune response and virulence factor production. Their cellular levels in bacteria are fine-tuned by metal-dependent phosphodiesterases, namely, the EAL and HD-GYP proteins, with HD-GYPs belonging to the larger HD d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochemistry
Hauptverfasser: Sun, Sining, Pandelia, Maria-Eirini
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8177754/
https://ncbi.nlm.nih.gov/pubmed/32496757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00257
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