Distinct PD-L1 binding characteristics of therapeutic monoclonal antibody durvalumab

Eitemau Tebyg

• Crystal clear: visualizing the intervention mechanism of the PD-1/PD-L1 interaction by two cancer therapeutic monoclonal antibodies
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• Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy
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  Cyhoeddwyd: (2017)
• The FG Loop of PD-1 Serves as a “Hotspot” for Therapeutic Monoclonal Antibodies in Tumor Immune Checkpoint Therapy
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  Cyhoeddwyd: (2019)
• Remarkably similar CTLA-4 binding properties of therapeutic ipilimumab and tremelimumab antibodies
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  Cyhoeddwyd: (2017)
• Glycosylation-independent binding of monoclonal antibody toripalimab to FG loop of PD-1 for tumor immune checkpoint therapy
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  Cyhoeddwyd: (2019)