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Remarkably similar CTLA-4 binding properties of therapeutic ipilimumab and tremelimumab antibodies
Monoclonal antibody based immune checkpoint blockade therapies have achieved clinical successes in management of malignant tumors. As the first monoclonal antibody targeting immune checkpoint molecules entered into clinics, the molecular basis of ipilimumab-based anti-CTLA-4 blockade has not yet bee...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5620161/ https://ncbi.nlm.nih.gov/pubmed/28978021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18004 |
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