Gemcitabine, a broad-spectrum antiviral drug, suppresses enterovirus infections through innate immunity induced by the inhibition of pyrimidine biosynthesis and nucleotide depletion

Gemcitabine, an anti-cancer chemotherapy drug, has additionally shown the antiviral activity against a broad range of viruses and we also have previously reported its synergistic antiviral activity with ribavirin against enteroviruses. As a cytidine analog, gemcitabine has been reported to have an i...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Lee, Kyungjin, Kim, Dong-Eun, Jang, Kyoung-Soon, Kim, Seong-Jun, Cho, Sungchan, Kim, Chonsaeng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777774/
https://ncbi.nlm.nih.gov/pubmed/29383162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23258
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