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Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis
Compound A3 was identified in a high-throughput screen for inhibitors of influenza virus replication. It displays broad-spectrum antiviral activity, and at noncytotoxic concentrations it is shown to inhibit the replication of negative-sense RNA viruses (influenza viruses A and B, Newcastle disease v...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3078400/ https://ncbi.nlm.nih.gov/pubmed/21436031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101143108 |
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