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INO80 haploinsufficiency inhibits colon cancer tumorigenesis via replication stress-induced apoptosis
The INO80 chromatin-remodeling complex performs functions in many chromosomal processes that are crucial for genome stability, such as DNA replication and stalled replication fork recovery. Although these functions suggest that INO80 acts as a tumor suppressor, its specific role in tumorigenesis has...
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| Udgivet i: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Impact Journals LLC
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5777752/ https://ncbi.nlm.nih.gov/pubmed/29383140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22984 |
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