Genetic variation in the NEIL2 DNA glycosylase gene is associated with oxidative DNA damage in BRCA2 mutation carriers

In this report, we have tried to gain molecular insight into a single nucleotide polymorphism (SNP) in the NEIL2 gene previously identified as “cancer risk modifier” for BRCA2 mutation carriers. To that end, we studied the role of this SNP (rs804271) on NEIL2 transcriptional regulation, oxidative DN...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Benítez-Buelga, Carlos, Baquero, Juan Miguel, Vaclova, Tereza, Fernández, Victoria, Martín, Paloma, Inglada-Perez, Lucia, Urioste, Miguel, Osorio, Ana, Benítez, Javier
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777719/
https://ncbi.nlm.nih.gov/pubmed/29383107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22638
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