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Molecular insights into the OGG1 gene, a cancer risk modifier in BRCA1 and BRCA2 mutations carriers

We have recently shown that rs2304277 variant in the OGG1 glycosidase gene of the Base Excision Repair pathway can increase ovarian cancer risk in BRCA1 mutation carriers. In the present study, we aimed to explore the role of this genetic variant on different genome instability hallmarks to explain...

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Foilsithe in:Oncotarget
Main Authors: Benitez-Buelga, Carlos, Vaclová, Tereza, Ferreira, Sofia, Urioste, Miguel, Inglada-Perez, Lucia, Soberón, Nora, Blasco, Maria A., Osorio, Ana, Benitez, Javier
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041946/
https://ncbi.nlm.nih.gov/pubmed/27015555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8272
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