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Molecular insights into the OGG1 gene, a cancer risk modifier in BRCA1 and BRCA2 mutations carriers

We have recently shown that rs2304277 variant in the OGG1 glycosidase gene of the Base Excision Repair pathway can increase ovarian cancer risk in BRCA1 mutation carriers. In the present study, we aimed to explore the role of this genetic variant on different genome instability hallmarks to explain...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Benitez-Buelga, Carlos, Vaclová, Tereza, Ferreira, Sofia, Urioste, Miguel, Inglada-Perez, Lucia, Soberón, Nora, Blasco, Maria A., Osorio, Ana, Benitez, Javier
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5041946/
https://ncbi.nlm.nih.gov/pubmed/27015555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8272
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