YAP regulates PD-L1 expression in human NSCLC cells

Programmed death-ligand 1 (PD-L1) is a membrane protein on tumor cells that binds to the PD-1 receptor expressed on immune cells, leading to the immune escape of tumor cells. Yes-associated protein (YAP) is a main effector of the Hippo/YAP signaling pathway, which plays important roles in cancer dev...

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Vydáno v:Oncotarget
Hlavní autoři: Miao, Jinbai, Hsu, Ping-Chih, Yang, Yi-Lin, Xu, Zhidong, Dai, Yuyuan, Wang, Yucheng, Chan, Geraldine, Huang, Zhen, Hu, Bin, Li, Hui, Jablons, David M., You, Liang
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777715/
https://ncbi.nlm.nih.gov/pubmed/29383103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23051
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