YAP promotes erlotinib resistance in human non-small cell lung cancer cells

Yes-associated protein (YAP) is a main mediator of the Hippo pathway, which promotes cancer development. Here we show that YAP promotes resistance to erlotinib in human non-small cell lung cancer (NSCLC) cells. We found that forced YAP overexpression through YAP plasmid transfection promotes erlotin...

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Foilsithe in:Oncotarget
Main Authors: Hsu, Ping-Chih, You, Bin, Yang, Yi-Lin, Zhang, Wen-Qian, Wang, Yu-Cheng, Xu, Zhidong, Dai, Yuyuan, Liu, Shu, Yang, Cheng-Ta, Li, Hui, Hu, Bin, Jablons, David M., You, Liang
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2016
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5239524/
https://ncbi.nlm.nih.gov/pubmed/27409162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10458
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