Sleep Dysfunction and EEG Alterations in Mice Overexpressing Alpha-Synuclein

BACKGROUND: Sleep disruptions occur early and frequently in Parkinson’s disease (PD). PD patients also show a slowing of resting state activity. Alpha-synuclein is causally linked to PD and accumulates in sleep-related brain regions. While sleep problems occur in over 75% of PD patients and severely...

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Bibliographic Details
Published in:J Parkinsons Dis
Main Authors: McDowell, Kimberly A., Shin, David, Roos, Kenneth P., Chesselet, Marie-Françoise
Format: Artigo
Language:Inglês
Published: IOS Press 2018
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Research Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777499/
https://ncbi.nlm.nih.gov/pubmed/24867919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-140374
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