Epitranscriptomic m(6)A Regulation of Axon Regeneration in the Adult Mammalian Nervous System

N(6)-methyladenosine (m(6)A) affects multiple aspects of mRNA metabolism and regulates developmental transitions by promoting mRNA decay. Little is known about the role of m(6)A in the adult mammalian nervous system. Here we report that sciatic nerve lesion elevates levels of m(6)A-tagged transcript...

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Pubblicato in:Neuron
Autori principali: Weng, Yi-Lan, Wang, Xu, An, Ran, Cassin, Jessica, Vissers, Caroline, Liu, Yuanyuan, Liu, Yajing, Xu, Tianlei, Wang, Xinyuan, Wong, Samuel Zheng Hao, Joseph, Jessica, Dore, Louis C., Dong, Qiang, Zheng, Wei, Jin, Peng, Wu, Hao, Shen, Bin, Zhuang, Xiaoxi, He, Chuan, Liu, Kai, Song, Hongjun, Ming, Guo-li
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777326/
https://ncbi.nlm.nih.gov/pubmed/29346752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.12.036
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