Epitranscriptomic m(6)A Regulation of Axon Regeneration in the Adult Mammalian Nervous System

N(6)-methyladenosine (m(6)A) affects multiple aspects of mRNA metabolism and regulates developmental transitions by promoting mRNA decay. Little is known about the role of m(6)A in the adult mammalian nervous system. Here we report that sciatic nerve lesion elevates levels of m(6)A-tagged transcript...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Weng, Yi-Lan, Wang, Xu, An, Ran, Cassin, Jessica, Vissers, Caroline, Liu, Yuanyuan, Liu, Yajing, Xu, Tianlei, Wang, Xinyuan, Wong, Samuel Zheng Hao, Joseph, Jessica, Dore, Louis C., Dong, Qiang, Zheng, Wei, Jin, Peng, Wu, Hao, Shen, Bin, Zhuang, Xiaoxi, He, Chuan, Liu, Kai, Song, Hongjun, Ming, Guo-li
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777326/
https://ncbi.nlm.nih.gov/pubmed/29346752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.12.036
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