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Ribosomal Synthesis of Thioether-Bridged Bicyclic Peptides

Many biologically active peptides found in nature exhibit a bicyclic structure wherein a head-to-tail cyclic backbone is further constrained by an intramolecular linkage connecting two side chains of the peptide. Accordingly, methods to access macrocyclic peptides sharing this overall topology could...

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Publicat a:Methods Mol Biol
Autors principals: Bionda, Nina, Fasan, Rudi
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777217/
https://ncbi.nlm.nih.gov/pubmed/27714610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6451-2_5
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