ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations

ATM (ataxia-telangiectasia mutated) and ATR (ATM and Rad3-related) are large PI3 kinases whose human mutations result in complex syndromes that include a compromised DNA damage response (DDR) and prominent nervous system phenotypes. Both proteins are nuclear-localized in keeping with their DDR funct...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Cheng, Aifang, Zhao, Teng, Tse, Kai-Hei, Chow, Hei-Man, Cui, Yong, Jiang, Liwen, Du, Shengwang, Loy, Michael M. T., Herrup, Karl
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777069/
https://ncbi.nlm.nih.gov/pubmed/29279380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716892115
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