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SbcC-SbcD and ExoI process convergent forks to complete chromosome replication

SbcC-SbcD are the bacterial orthologs of Mre11-Rad50, a nuclease complex essential for genome stability, normal development, and viability in mammals. In vitro, these enzymes degrade long DNA palindromic structures. When inactivated along with ExoI in Escherichia coli, or Sae2 in eukaryotes, palindr...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Wendel, Brian M., Cole, Jessica M., Courcelle, Charmain T., Courcelle, Justin
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777064/
https://ncbi.nlm.nih.gov/pubmed/29208713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715960114
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