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RecBCD, SbcCD and ExoI process a substrate created by convergent replisomes to complete DNA replication

The accurate completion of DNA replication on the chromosome requires RecBCD and structure specific SbcCD ExoI nucleases. However, the substrates and mechanism by which this reaction occurs remains unknown. Here we show that these completion enzymes operate on plasmid substrates containing two repli...

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Detalhes bibliográficos
Publicado no:Mol Microbiol
Main Authors: Hamilton, Nicklas A., Wendel, Brian M., Weber, Emma A., Courcelle, Charmain T., Courcelle, Justin
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561825/
https://ncbi.nlm.nih.gov/pubmed/30883946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14242
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