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RSK2 drives cell motility by serine phosphorylation of LARG and activation of Rho GTPases

Directed migration is essential for cell motility in many processes, including development and cancer cell invasion. RSKs (p90 ribosomal S6 kinases) have emerged as central regulators of cell migration; however, the mechanisms mediating RSK-dependent motility remain incompletely understood. We have...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Shi, Geng-Xian, Yang, Won Seok, Jin, Ling, Matter, Michelle L., Ramos, Joe W.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777029/
https://ncbi.nlm.nih.gov/pubmed/29279389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708584115
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