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RSK2 drives cell motility by serine phosphorylation of LARG and activation of Rho GTPases

Directed migration is essential for cell motility in many processes, including development and cancer cell invasion. RSKs (p90 ribosomal S6 kinases) have emerged as central regulators of cell migration; however, the mechanisms mediating RSK-dependent motility remain incompletely understood. We have...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Shi, Geng-Xian, Yang, Won Seok, Jin, Ling, Matter, Michelle L., Ramos, Joe W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777029/
https://ncbi.nlm.nih.gov/pubmed/29279389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1708584115
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