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Silk-based multilayered angle-ply annulus fibrosus construct to recapitulate form and function of the intervertebral disc

Recapitulation of the form and function of complex tissue organization using appropriate biomaterials impacts success in tissue engineering endeavors. The annulus fibrosus (AF) represents a complex, multilamellar, hierarchical structure consisting of collagen, proteoglycans, and elastic fibers. To m...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bhunia, Bibhas K., Kaplan, David L., Mandal, Biman B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776988/
https://ncbi.nlm.nih.gov/pubmed/29282316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715912115
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