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Silk-based multilayered angle-ply annulus fibrosus construct to recapitulate form and function of the intervertebral disc

Recapitulation of the form and function of complex tissue organization using appropriate biomaterials impacts success in tissue engineering endeavors. The annulus fibrosus (AF) represents a complex, multilamellar, hierarchical structure consisting of collagen, proteoglycans, and elastic fibers. To m...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Bhunia, Bibhas K., Kaplan, David L., Mandal, Biman B.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776988/
https://ncbi.nlm.nih.gov/pubmed/29282316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715912115
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