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Silk-based multilayered angle-ply annulus fibrosus construct to recapitulate form and function of the intervertebral disc

Recapitulation of the form and function of complex tissue organization using appropriate biomaterials impacts success in tissue engineering endeavors. The annulus fibrosus (AF) represents a complex, multilamellar, hierarchical structure consisting of collagen, proteoglycans, and elastic fibers. To m...

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發表在:Proc Natl Acad Sci U S A
Main Authors: Bhunia, Bibhas K., Kaplan, David L., Mandal, Biman B.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776988/
https://ncbi.nlm.nih.gov/pubmed/29282316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715912115
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