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Cytotoxic effect of Efavirenz in BxPC-3 pancreatic cancer cells is based on oxidative stress and is synergistic with ionizing radiation

The non-nucleoside reverse transcriptase inhibitor (NNRTI) Efavirenz is frequently used in human immunodeficiency virus treatment, but also efficient against cancer in mouse models. Its radiosensitizing effect makes it a promising drug for combination with radiotherapy. The efficacy of Efavirenz com...

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Bibliografiska uppgifter
I publikationen:Oncol Lett
Huvudupphovsmän: Hecht, Markus, Harrer, Thomas, Körber, Verena, Sarpong, Eric O., Moser, Fabian, Fiebig, Nora, Schwegler, Manuela, Stürzl, Michael, Fietkau, Rainer, Distel, Luitpold V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: D.A. Spandidos 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776903/
https://ncbi.nlm.nih.gov/pubmed/29434868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7523
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