Efavirenz Has the Highest Anti-Proliferative Effect of Non-Nucleoside Reverse Transcriptase Inhibitors against Pancreatic Cancer Cells

BACKGROUND: Cancer prevention and therapy in HIV-1-infected patients will play an important role in future. The non-nucleoside reverse transcriptase inhibitors (NNRTI) Efavirenz and Nevirapine are cytotoxic against cancer cells in vitro. As other NNRTIs have not been studied so far, all clinically u...

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Pubblicato in:PLoS One
Autori principali: Hecht, Markus, Erber, Sonja, Harrer, Thomas, Klinker, Hartwig, Roth, Thomas, Parsch, Hans, Fiebig, Nora, Fietkau, Rainer, Distel, Luitpold V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4473268/
https://ncbi.nlm.nih.gov/pubmed/26086472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130277
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