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Deficient repair of 8-hydroxyguanine in the BxPC-3 pancreatic cancer cell line

Elevated levels of oxidatively induced DNA lesions have been reported in malignant pancreatic tissues relative to normal pancreatic tissues. However, the ability of the pancreatic cancer cells to remove these lesions has not previously been addressed. This study analyzed the effectiveness of the pan...

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Bibliographic Details
Main Authors: Nyaga, Simon G., Lohani, Althaf, Evans, Michele K.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699024/
https://ncbi.nlm.nih.gov/pubmed/18774780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.08.134
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