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Deficient repair of 8-hydroxyguanine in the BxPC-3 pancreatic cancer cell line

Elevated levels of oxidatively induced DNA lesions have been reported in malignant pancreatic tissues relative to normal pancreatic tissues. However, the ability of the pancreatic cancer cells to remove these lesions has not previously been addressed. This study analyzed the effectiveness of the pan...

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Detalhes bibliográficos
Main Authors: Nyaga, Simon G., Lohani, Althaf, Evans, Michele K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699024/
https://ncbi.nlm.nih.gov/pubmed/18774780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.08.134
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