Osteopontin deletion drives hematopoietic stem cell mobilization to the liver and increases hepatic iron contributing to alcoholic liver disease

The aim of this study was to investigate the role of osteopontin (OPN) in hematopoietic stem cell (HPSC) mobilization to the liver and its contribution to alcoholic liver disease (ALD). We analyzed young (14‐16 weeks) and old (>1.5 years) wild‐type (WT) littermates and global Opn knockout (Opn(−/...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Hepatol Commun
Hauptverfasser: Magdaleno, Fernando, Ge, Xiaodong, Fey, Holger, Lu, Yongke, Gaskell, Harriet, Blajszczak, Chuck C., Aloman, Costica, Fiel, M. Isabel, Nieto, Natalia
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776866/
https://ncbi.nlm.nih.gov/pubmed/29404515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1116
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge