Tanshinone IIA inhibits AGEs-induced proliferation and migration of cultured vascular smooth muscle cells by suppressing ERK1/2 MAPK signaling

OBJECTIVE(S): Vascular smooth muscle cells (VSMCs) play a key role in the pathogenesis of diabetic vascular disease. Our current study sought to explore the effects of tanshinone IIA on the proliferation and migration of VSMCs induced by advanced glycation end products (AGEs). MATERIALS AND METHODS:...

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Vydáno v:Iran J Basic Med Sci
Hlavní autoři: Lu, Ming, Luo, Ying, Hu, Pengfei, Dou, Liping, Huang, Shuwei
Médium: Artigo
Jazyk:Inglês
Vydáno: Mashhad University of Medical Sciences 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776441/
https://ncbi.nlm.nih.gov/pubmed/29372041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/IJBMS.2017.20100.5276
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