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Tanshinone IIA inhibits AGEs-induced proliferation and migration of cultured vascular smooth muscle cells by suppressing ERK1/2 MAPK signaling

OBJECTIVE(S): Vascular smooth muscle cells (VSMCs) play a key role in the pathogenesis of diabetic vascular disease. Our current study sought to explore the effects of tanshinone IIA on the proliferation and migration of VSMCs induced by advanced glycation end products (AGEs). MATERIALS AND METHODS:...

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Pubblicato in:Iran J Basic Med Sci
Autori principali: Lu, Ming, Luo, Ying, Hu, Pengfei, Dou, Liping, Huang, Shuwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mashhad University of Medical Sciences 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776441/
https://ncbi.nlm.nih.gov/pubmed/29372041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/IJBMS.2017.20100.5276
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