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Tanshinone IIA inhibits AGEs-induced proliferation and migration of cultured vascular smooth muscle cells by suppressing ERK1/2 MAPK signaling

OBJECTIVE(S): Vascular smooth muscle cells (VSMCs) play a key role in the pathogenesis of diabetic vascular disease. Our current study sought to explore the effects of tanshinone IIA on the proliferation and migration of VSMCs induced by advanced glycation end products (AGEs). MATERIALS AND METHODS:...

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Detalhes bibliográficos
Publicado no:Iran J Basic Med Sci
Main Authors: Lu, Ming, Luo, Ying, Hu, Pengfei, Dou, Liping, Huang, Shuwei
Formato: Artigo
Idioma:Inglês
Publicado em: Mashhad University of Medical Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776441/
https://ncbi.nlm.nih.gov/pubmed/29372041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/IJBMS.2017.20100.5276
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