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Novel frameshift mutation in the KCNQ1 gene responsible for Jervell and Lange-Nielsen syndrome

OBJECTIVE(S): Jervell and Lange–Nielsen syndrome is an autosomal recessive disorder caused by mutations in KCNQ1 or KCNE1 genes. The disease is characterized by sensorineural hearing loss and long QT syndrome. MATERIALS AND METHODS: Here we present a 3.5-year-old female patient, an offspring of cons...

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Dettagli Bibliografici
Pubblicato in:Iran J Basic Med Sci
Autori principali: Amirian, Azam, Dalili, Seyed Mohammad, Zafari, Zahra, Saber, Siamak, Karimipoor, Morteza, Akbari, Vahid, Fazelifar, Amir Farjam, Zeinali, Sirous
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mashhad University of Medical Sciences 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776430/
https://ncbi.nlm.nih.gov/pubmed/29372044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/IJBMS.2017.23207.5908
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