Phosphorylation of the Transient Receptor Potential Ankyrin 1 by Cyclin-dependent Kinase 5 affects Chemo-nociception

Cyclin-dependent kinase 5 (Cdk5) is a key neuronal kinase that is upregulated during inflammation, and can subsequently modulate sensitivity to nociceptive stimuli. We conducted an in silico screen for Cdk5 phosphorylation sites within proteins whose expression was enriched in nociceptors and identi...

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Vydáno v:Sci Rep
Hlavní autoři: Hall, Bradford E., Prochazkova, Michaela, Sapio, Matthew R., Minetos, Paul, Kurochkina, Natalya, Binukumar, B. K., Amin, Niranjana D., Terse, Anita, Joseph, John, Raithel, Stephen J., Mannes, Andrew J., Pant, Harish C., Chung, Man-Kyo, Iadarola, Michael J., Kulkarni, Ashok B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775258/
https://ncbi.nlm.nih.gov/pubmed/29352128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19532-6
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