Phosphorylation of the Transient Receptor Potential Ankyrin 1 by Cyclin-dependent Kinase 5 affects Chemo-nociception

Cyclin-dependent kinase 5 (Cdk5) is a key neuronal kinase that is upregulated during inflammation, and can subsequently modulate sensitivity to nociceptive stimuli. We conducted an in silico screen for Cdk5 phosphorylation sites within proteins whose expression was enriched in nociceptors and identi...

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Publicado en:Sci Rep
Main Authors: Hall, Bradford E., Prochazkova, Michaela, Sapio, Matthew R., Minetos, Paul, Kurochkina, Natalya, Binukumar, B. K., Amin, Niranjana D., Terse, Anita, Joseph, John, Raithel, Stephen J., Mannes, Andrew J., Pant, Harish C., Chung, Man-Kyo, Iadarola, Michael J., Kulkarni, Ashok B.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775258/
https://ncbi.nlm.nih.gov/pubmed/29352128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19532-6
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