Phosphorylation of the Transient Receptor Potential Ankyrin 1 by Cyclin-dependent Kinase 5 affects Chemo-nociception

Cyclin-dependent kinase 5 (Cdk5) is a key neuronal kinase that is upregulated during inflammation, and can subsequently modulate sensitivity to nociceptive stimuli. We conducted an in silico screen for Cdk5 phosphorylation sites within proteins whose expression was enriched in nociceptors and identi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hall, Bradford E., Prochazkova, Michaela, Sapio, Matthew R., Minetos, Paul, Kurochkina, Natalya, Binukumar, B. K., Amin, Niranjana D., Terse, Anita, Joseph, John, Raithel, Stephen J., Mannes, Andrew J., Pant, Harish C., Chung, Man-Kyo, Iadarola, Michael J., Kulkarni, Ashok B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775258/
https://ncbi.nlm.nih.gov/pubmed/29352128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19532-6
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