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Multiplex Aptamer Discovery through Apta-Seq and Its Application to ATP Aptamers Derived from Human-Genomic SELEX

Laboratory-evolved RNAs bind a wide variety of targets and serve highly diverse functions, including as diagnostic and therapeutic aptamers. The majority of aptamers have been identified using in vitro selection (SELEX), a molecular evolution technique based on selecting target-binding RNAs from hig...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Abdelsayed, Michael M., Ho, Bao T., Vu, Michael M. K., Polanco, Julio, Spitale, Robert C., Lupták, Andrej
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5775184/
https://ncbi.nlm.nih.gov/pubmed/28661647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00001
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