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Discovery of Aptamer Ligands for Hepatic Stellate Cells Using SELEX

Insulin like growth factor II receptor (IGFIIR) is a transmembrane protein overexpressed in activated hepatic stellate cells (HSCs), which are the major target for the treatment of liver fibrosis. In this study, we aim to discover an IGFIIR-specific aptamer that can be potentially used as a targetin...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Chen, Zhijin, Liu, Hao, Jain, Akshay, Zhang, Li, Liu, Chang, Cheng, Kun
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566100/
https://ncbi.nlm.nih.gov/pubmed/28839458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.19374
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