Single-Dose Trivalent VesiculoVax Vaccine Protects Macaques from Lethal Ebolavirus and Marburgvirus Challenge

Previous studies demonstrated that a single intramuscular (i.m.) dose of an attenuated recombinant vesicular stomatitis virus (rVSV) vector (VesiculoVax vector platform; rVSV-N4CT1) expressing the glycoprotein (GP) from the Mayinga strain of Zaire ebolavirus (EBOV) protected nonhuman primates (NHPs)...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Matassov, Demetrius, Mire, Chad E., Latham, Theresa, Geisbert, Joan B., Xu, Rong, Ota-Setlik, Ayuko, Agans, Krystle N., Kobs, Dean J., Wendling, Morgan Q. S., Burnaugh, Amanda, Rudge, Thomas L., Sabourin, Carol L., Egan, Michael A., Clarke, David K., Geisbert, Thomas W., Eldridge, John H.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2018
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774882/
https://ncbi.nlm.nih.gov/pubmed/29142131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01190-17
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