A Single-Vector, Single-Injection Trivalent Filovirus Vaccine: Proof of Concept Study in Outbred Guinea Pigs

The filoviruses, Marburg marburgvirus (MARV), Zaire ebolavirus (ZEBOV), and Sudan ebolavirus (SEBOV), cause severe and often fatal hemorrhagic fever in humans and nonhuman primates (NHPs). Monovalent recombinant vesicular stomatitis virus (rVSV)–based vaccine vectors, which encode a filovirus glycop...

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Dettagli Bibliografici
Pubblicato in:J Infect Dis
Autori principali: Mire, Chad E., Geisbert, Joan B., Versteeg, Krista M., Mamaeva, Natalia, Agans, Krystle N., Geisbert, Thomas W., Connor, John H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Ebola and Marburg Viruses-Research, Outbreak Management, Epidemiology and Ecology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564539/
https://ncbi.nlm.nih.gov/pubmed/25957964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv126
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