A Single-Vector, Single-Injection Trivalent Filovirus Vaccine: Proof of Concept Study in Outbred Guinea Pigs

The filoviruses, Marburg marburgvirus (MARV), Zaire ebolavirus (ZEBOV), and Sudan ebolavirus (SEBOV), cause severe and often fatal hemorrhagic fever in humans and nonhuman primates (NHPs). Monovalent recombinant vesicular stomatitis virus (rVSV)–based vaccine vectors, which encode a filovirus glycop...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Mire, Chad E., Geisbert, Joan B., Versteeg, Krista M., Mamaeva, Natalia, Agans, Krystle N., Geisbert, Thomas W., Connor, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Ebola and Marburg Viruses-Research, Outbreak Management, Epidemiology and Ecology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564539/
https://ncbi.nlm.nih.gov/pubmed/25957964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv126
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