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Quadrivalent VesiculoVax vaccine protects nonhuman primates from viral-induced hemorrhagic fever and death

Recent occurrences of filoviruses and the arenavirus Lassa virus (LASV) in overlapping endemic areas of Africa highlight the need for a prophylactic vaccine that would confer protection against all of these viruses that cause lethal hemorrhagic fever (HF). We developed a quadrivalent formulation of...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Cross, Robert W., Xu, Rong, Matassov, Demetrius, Hamm, Stefan, Latham, Theresa E., Gerardi, Cheryl S., Nowak, Rebecca M., Geisbert, Joan B., Ota-Setlik, Ayuko, Agans, Krystle N., Luckay, Amara, Witko, Susan E., Soukieh, Lena, Deer, Daniel J., Mire, Chad E., Feldmann, Heinz, Happi, Christian, Fenton, Karla A., Eldridge, John H., Geisbert, Thomas W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6934204/
https://ncbi.nlm.nih.gov/pubmed/31820871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI131958
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