Prognostic and predictive role of EGFR pathway alterations in biliary cancer patients treated with chemotherapy and anti-EGFR

The association of anti-EGFR to gemcitabine and oxaliplatin (GEMOX) chemotherapy did not improve survival in biliary tract carcinoma (BTC) patients. Multiple mechanisms might be involved in the resistance to anti-EGFR. Here, we explored the mutation profile of EGFR extracellular domain (ECD), of tyr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Peraldo-Neia, Caterina, Cavalloni, Giuliana, Fenocchio, Elisabetta, Cagnazzo, Celeste, Gammaitoni, Loretta, Cereda, Stefano, Nasti, Guglielmo, Satolli, Maria Antonietta, Aprile, Giuseppe, Reni, Michele, Avallone, Antonio, Spadi, Rosella, Venesio, Tiziana, Martin, Vittoria, Doglioni, Claudio, Frattini, Milo, Aglietta, Massimo, Leone, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774843/
https://ncbi.nlm.nih.gov/pubmed/29352306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191593
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados