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An Ichor-dependent apical extracellular matrix regulates seamless tube shape and integrity

During sprouting angiogenesis in the vertebrate vascular system, and primary branching in the Drosophila tracheal system, specialized tip cells direct branch outgrowth and network formation. When tip cells lumenize, they form subcellular (seamless) tubes. How these seamless tubes are made, shaped an...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Rosa, Jeffrey B., Metzstein, Mark M., Ghabrial, Amin S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774827/
https://ncbi.nlm.nih.gov/pubmed/29309404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007146
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